This article is for the CAT LOVERS……if you are not in this select group, please go to next post. You are warned.

kofegeek

Genetic studies conclude that cats cannot sense “sweetness”. Not only cat actually, but also most of its family such as tiger, lion, and cheetah. They are unable to recognize sweet taste; although “attractive” and “tasting” ability are used for mammals to detect calories.

Researchers looked into the genetic of cat family and found that they lack the 247 pairs of genetics called Tas1r2 gene, which encodes T1R2, one of two protein subunits that make the sweet taste receptor in most mammals. Scientists prejudiced that the protein was functioning in the common ancestor of the cat, but not anymore. Meanwhile, the partner subunit, namely T1R3, can function well.

Mammalian sweet-taste receptor is formed by the dimerization of two proteins (T1R2 and T1R3; gene symbols Tas1r2 and Tas1r3), scientist identified and sequenced both genes in the cat.  The cat Tas1r3 gene shows high sequence similarity with functional Tas1r3 genes of other species. In situ hybridization and immunohistochemical studies demonstrate that Tas1r3 is expressed, as expected, in taste buds. However, the cat Tas1r2 gene shows a 247-base pair microdeletion in exon 3 and stop codons in exons 4 and 6. There was no evidence of detectable mRNA from catTas1r2, and…

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